BRD-A45498368_WYE-125132_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-A45498368_WYE-125132_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
ARID5B AT rich interactive domain 5B (MRF1-like)
BASP1 brain abundant, membrane attached signal protein 1
CBR3 carbonyl reductase 3
CCL5 chemokine (C-C motif) ligand 5
CD52 CD52 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHN1 chimerin 1
CXCL12 chemokine (C-X-C motif) ligand 12
EFNA1 ephrin-A1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FKBP11 FK506 binding protein 11, 19 kDa
FOXO3 forkhead box O3
FXYD3 FXYD domain containing ion transport regulator 3
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IL7R interleukin 7 receptor
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0355 KIAA0355
KIAA1033 KIAA1033
KLF2 Kruppel-like factor 2
MBNL2 muscleblind-like splicing regulator 2
MECOM MDS1 and EVI1 complex locus
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
SPAG4 sperm associated antigen 4
SYNE2 spectrin repeat containing, nuclear envelope 2
TGIF1 TGFB-induced factor homeobox 1
TRBC1 T cell receptor beta constant 1
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
VCAN versican

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CKLF chemokine-like factor
COL1A2 collagen, type I, alpha 2
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEFB1 defensin, beta 1
ELANE elastase, neutrophil expressed
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HBB hemoglobin, beta
HSPA1A heat shock 70kDa protein 1A
KLK10 kallikrein-related peptidase 10
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPEN spen family transcriptional repressor
SPP1 secreted phosphoprotein 1