BRD-A45498368_WYE-125132_SKBR3_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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83 genes differentially expressed following the BRD-A45498368_WYE-125132_SKBR3_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOLD1 apolipoprotein L domain containing 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
BACE2 beta-site APP-cleaving enzyme 2
BICC1 BicC family RNA binding protein 1
BZW2 basic leucine zipper and W2 domains 2
CCDC28A coiled-coil domain containing 28A
CD81 CD81 molecule
CRIP1 cysteine-rich protein 1 (intestinal)
CSNK1E casein kinase 1, epsilon
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
HNMT histamine N-methyltransferase
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
IRS2 insulin receptor substrate 2
JMJD1C jumonji domain containing 1C
KDM3A lysine (K)-specific demethylase 3A
KIAA0355 KIAA0355
KLF6 Kruppel-like factor 6
LAMP2 lysosomal-associated membrane protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAB21L2 mab-21-like 2 (C. elegans)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MFAP5 microfibrillar associated protein 5
MT2A metallothionein 2A
NRBF2 nuclear receptor binding factor 2
PDGFA platelet-derived growth factor alpha polypeptide
PER2 period circadian clock 2
PIP prolactin-induced protein
PLCB4 phospholipase C, beta 4
RALBP1 ralA binding protein 1
RCAN1 regulator of calcineurin 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3BP4 SH3-domain binding protein 4
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF6 serine/arginine-rich splicing factor 6
TNS1 tensin 1
TOB1 transducer of ERBB2, 1
TSC22D3 TSC22 domain family, member 3
TSPAN5 tetraspanin 5
TSPAN8 tetraspanin 8
TXN thioredoxin

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
ALB albumin
APOB apolipoprotein B
BAG3 BCL2-associated athanogene 3
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CNN3 calponin 3, acidic
DCT dopachrome tautomerase
ESR1 estrogen receptor 1
FHL2 four and a half LIM domains 2
FOLR1 folate receptor 1 (adult)
GAL galanin/GMAP prepropeptide
GRIA2 glutamate receptor, ionotropic, AMPA 2
GYG1 glycogenin 1
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
LAPTM4B lysosomal protein transmembrane 4 beta
MAMLD1 mastermind-like domain containing 1
MLEC malectin
NELL2 NEL-like 2 (chicken)
PFN2 profilin 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPAG4 sperm associated antigen 4
SVIL supervillin
TF transferrin
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WT1 Wilms tumor 1