BRD-A45498368_WYE-125132_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-A45498368_WYE-125132_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP9A ATPase, class II, type 9A
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFD complement factor D (adipsin)
CHL1 cell adhesion molecule L1-like
CRIP1 cysteine-rich protein 1 (intestinal)
CTSK cathepsin K
DAPK1 death-associated protein kinase 1
DUSP4 dual specificity phosphatase 4
GABARAPL1 GABA(A) receptor-associated protein like 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HIST1H2BG histone cluster 1, H2bg
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTUS1 microtubule associated tumor suppressor 1
MXRA5 matrix-remodelling associated 5
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRN1 neuritin 1
OAT ornithine aminotransferase
PDGFRL platelet-derived growth factor receptor-like
PROS1 protein S (alpha)
PSAP prosaposin
PSPH phosphoserine phosphatase
RGS1 regulator of G-protein signaling 1
SCGB2A2 secretoglobin, family 2A, member 2
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STOM stomatin
TGIF1 TGFB-induced factor homeobox 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC22D3 TSC22 domain family, member 3
VIM vimentin
ZNF217 zinc finger protein 217
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ALB albumin
BAG3 BCL2-associated athanogene 3
BEX1 brain expressed, X-linked 1
C4BPA complement component 4 binding protein, alpha
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CTSC cathepsin C
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP7 dual specificity phosphatase 7
EIF5A eukaryotic translation initiation factor 5A
GAL galanin/GMAP prepropeptide
GPATCH8 G patch domain containing 8
GSTA1 glutathione S-transferase alpha 1
HSPA1A heat shock 70kDa protein 1A
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JADE2 jade family PHD finger 2
JAG1 jagged 1
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
MAMLD1 mastermind-like domain containing 1
MAOA monoamine oxidase A
NPTX2 neuronal pentraxin II
ORM1 orosomucoid 1
PFN2 profilin 2
PLAC8 placenta-specific 8
PLS1 plastin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RTN1 reticulon 1
S100A2 S100 calcium binding protein A2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TF transferrin