BRD-A45498368_WYE-125132_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A45498368_WYE-125132_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
AIM1 absent in melanoma 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANO1 anoctamin 1, calcium activated chloride channel
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
CFI complement factor I
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DMD dystrophin
DST dystonin
GCLC glutamate-cysteine ligase, catalytic subunit
GNLY granulysin
GSAP gamma-secretase activating protein
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER2 homer scaffolding protein 2
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IQCG IQ motif containing G
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LYPD1 LY6/PLAUR domain containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOB monoamine oxidase B
MREG melanoregulin
MSX1 msh homeobox 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBPC1 myosin binding protein C, slow type
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PECR peroxisomal trans-2-enoyl-CoA reductase
PEG3 paternally expressed 3
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SYNM synemin, intermediate filament protein
TACSTD2 tumor-associated calcium signal transducer 2
TPD52L1 tumor protein D52-like 1
TRH thyrotropin-releasing hormone
TSPAN4 tetraspanin 4

decreased expression

Symbol Name
CCND2 cyclin D2
CDC25A cell division cycle 25A
CNN3 calponin 3, acidic
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
FBXO28 F-box protein 28
FOLR1 folate receptor 1 (adult)
HBEGF heparin-binding EGF-like growth factor
JMJD6 jumonji domain containing 6
NVL nuclear VCP-like
NXT1 nuclear transport factor 2-like export factor 1
PIP prolactin-induced protein
PLAC8 placenta-specific 8
RAD23B RAD23 homolog B (S. cerevisiae)
TOX3 TOX high mobility group box family member 3
ZBTB18 zinc finger and BTB domain containing 18