BRD-A45498368_WYE-125132_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A45498368_WYE-125132_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AMDHD2 amidohydrolase domain containing 2
ARL4C ADP-ribosylation factor-like 4C
BHLHE40 basic helix-loop-helix family, member e40
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC25B cell division cycle 25B
CRYAB crystallin, alpha B
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
E2F2 E2F transcription factor 2
GPNMB glycoprotein (transmembrane) nmb
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
LOC100505650 uncharacterized LOC100505650
MX1 MX dynamin-like GTPase 1
NAV2 neuron navigator 2
NDRG1 N-myc downstream regulated 1
NEFL neurofilament, light polypeptide
NPC1 Niemann-Pick disease, type C1
NUPR1 nuclear protein, transcriptional regulator, 1
PAEP progestagen-associated endometrial protein
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDGFC platelet derived growth factor C
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SELENBP1 selenium binding protein 1
SFN stratifin
STC2 stanniocalcin 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TPBG trophoblast glycoprotein
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VCAN versican
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BANK1 B-cell scaffold protein with ankyrin repeats 1
C1ORF116 chromosome 1 open reading frame 116
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CDC25A cell division cycle 25A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CREB1 cAMP responsive element binding protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GAL galanin/GMAP prepropeptide
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNAS GNAS complex locus
GOLM1 golgi membrane protein 1
HN1 hematological and neurological expressed 1
LCN2 lipocalin 2
LTF lactotransferrin
MAOA monoamine oxidase A
MYBPC1 myosin binding protein C, slow type
NPY neuropeptide Y
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDE4B phosphodiesterase 4B, cAMP-specific
PYCARD PYD and CARD domain containing
SNAP25 synaptosomal-associated protein, 25kDa
SOBP sine oculis binding protein homolog (Drosophila)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TBX2 T-box 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TMPRSS2 transmembrane protease, serine 2