BRD-A45498368_WYE-125132_MDAMB231_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-A45498368_WYE-125132_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
BHLHE41 basic helix-loop-helix family, member e41
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CLDN1 claudin 1
CLIC5 chloride intracellular channel 5
CXCL2 chemokine (C-X-C motif) ligand 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
EFNA1 ephrin-A1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FXR1 fragile X mental retardation, autosomal homolog 1
GPX3 glutathione peroxidase 3
IFITM1 interferon induced transmembrane protein 1
INHBA inhibin, beta A
LAMP2 lysosomal-associated membrane protein 2
LYPD1 LY6/PLAUR domain containing 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPIPB3 nuclear pore complex interacting protein family, member B3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAU plasminogen activator, urokinase
RABAC1 Rab acceptor 1 (prenylated)
RPL36 ribosomal protein L36
RTN2 reticulon 2
SDCBP syndecan binding protein (syntenin)
SGK1 serum/glucocorticoid regulated kinase 1
SPARCL1 SPARC-like 1 (hevin)
SQSTM1 sequestosome 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I
TUBA1A tubulin, alpha 1a
YPEL5 yippee-like 5 (Drosophila)
ZC2HC1A zinc finger, C2HC-type containing 1A

decreased expression

Symbol Name
ADM adrenomedullin
AK4 adenylate kinase 4
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CCL19 chemokine (C-C motif) ligand 19
CDC25A cell division cycle 25A
CDKN3 cyclin-dependent kinase inhibitor 3
CKS2 CDC28 protein kinase regulatory subunit 2
CTPS1 CTP synthase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GINS1 GINS complex subunit 1 (Psf1 homolog)
H2AFX H2A histone family, member X
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB2 high mobility group box 2
ICMT isoprenylcysteine carboxyl methyltransferase
LMNB1 lamin B1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
PRC1 protein regulator of cytokinesis 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAD23B RAD23 homolog B (S. cerevisiae)
RCAN2 regulator of calcineurin 2
SCGB2A2 secretoglobin, family 2A, member 2
SLBP stem-loop binding protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPP1 secreted phosphoprotein 1
TOX3 TOX high mobility group box family member 3
TUBG1 tubulin, gamma 1
UBE2S ubiquitin-conjugating enzyme E2S
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZBTB18 zinc finger and BTB domain containing 18
ZWINT ZW10 interacting kinetochore protein