BRD-A45498368_WYE-125132_MCF7_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A45498368_WYE-125132_MCF7_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
C10ORF10 chromosome 10 open reading frame 10
C5 complement component 5
CCNG2 cyclin G2
CD14 CD14 molecule
COL11A1 collagen, type XI, alpha 1
CTSK cathepsin K
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
FAM129A family with sequence similarity 129, member A
FOLR1 folate receptor 1 (adult)
GPM6B glycoprotein M6B
HBP1 HMG-box transcription factor 1
HES1 hes family bHLH transcription factor 1
HSPA2 heat shock 70kDa protein 2
MFAP2 microfibrillar-associated protein 2
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBPF10 neuroblastoma breakpoint family, member 10
NRIP1 nuclear receptor interacting protein 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4B phosphodiesterase 4B, cAMP-specific
PERP PERP, TP53 apoptosis effector
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RGS1 regulator of G-protein signaling 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A9 S100 calcium binding protein A9
SCYL3 SCY1-like 3 (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
C2CD2 C2 calcium-dependent domain containing 2
CDC25A cell division cycle 25A
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMBT1 deleted in malignant brain tumors 1
EGFR epidermal growth factor receptor
EZR ezrin
FAS Fas cell surface death receptor
GATA2 GATA binding protein 2
HSPH1 heat shock 105kDa/110kDa protein 1
MALL mal, T-cell differentiation protein-like
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PFKP phosphofructokinase, platelet
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM34 RNA binding motif protein 34
RPP38 ribonuclease P/MRP 38kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
STAR steroidogenic acute regulatory protein
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b