BRD-A45498368_WYE-125132_MCF10A_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-A45498368_WYE-125132_MCF10A_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AHNAK AHNAK nucleoprotein
ALCAM activated leukocyte cell adhesion molecule
ANGPT1 angiopoietin 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA1 annexin A1
APOD apolipoprotein D
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAV2 caveolin 2
CCK cholecystokinin
CCNG2 cyclin G2
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CD59 CD59 molecule, complement regulatory protein
CFD complement factor D (adipsin)
CFH complement factor H
CHRDL1 chordin-like 1
CLU clusterin
CPVL carboxypeptidase, vitellogenic-like
CRYAB crystallin, alpha B
CXCL12 chemokine (C-X-C motif) ligand 12
CYB5A cytochrome b5 type A (microsomal)
CYTH1 cytohesin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
DSP desmoplakin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
ETNPPL ethanolamine-phosphate phospho-lyase
FBN1 fibrillin 1
FGF13 fibroblast growth factor 13
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
HBP1 HMG-box transcription factor 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB2 high mobility group box 2
HOPX HOP homeobox
IGF1R insulin-like growth factor 1 receptor
IGFBP6 insulin-like growth factor binding protein 6
IGFBP7 insulin-like growth factor binding protein 7
KIF14 kinesin family member 14
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KRT14 keratin 14, type I
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LIMCH1 LIM and calponin homology domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP2K5 mitogen-activated protein kinase kinase 5
MAP7 microtubule-associated protein 7
MET MET proto-oncogene, receptor tyrosine kinase
NAV2 neuron navigator 2
NEFH neurofilament, heavy polypeptide
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PERP PERP, TP53 apoptosis effector
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLS3 plastin 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A10 S100 calcium binding protein A10
SPARCL1 SPARC-like 1 (hevin)
SYNE2 spectrin repeat containing, nuclear envelope 2
TAGLN2 transgelin 2
TARP TCR gamma alternate reading frame protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
TXNIP thioredoxin interacting protein
ZIC1 Zic family member 1

decreased expression

Symbol Name
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CDC25A cell division cycle 25A
CDKN2A cyclin-dependent kinase inhibitor 2A
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
ITFG1 integrin alpha FG-GAP repeat containing 1
KLK10 kallikrein-related peptidase 10
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MZB1 marginal zone B and B1 cell-specific protein
NUPL1 nucleoporin like 1
PI3 peptidase inhibitor 3, skin-derived
RNF144A ring finger protein 144A
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SOBP sine oculis binding protein homolog (Drosophila)
SPAG4 sperm associated antigen 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
WT1 Wilms tumor 1
ZBED2 zinc finger, BED-type containing 2