BRD-A45498368_WYE-125132_MCF10A_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

78 genes differentially expressed following the BRD-A45498368_WYE-125132_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BST2 bone marrow stromal cell antigen 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CYTH1 cytohesin 1
DES desmin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
FLNB filamin B, beta
GRN granulin
HIST1H1C histone cluster 1, H1c
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
ITM2A integral membrane protein 2A
LGALS1 lectin, galactoside-binding, soluble, 1
LIMCH1 LIM and calponin homology domains 1
MYBPC1 myosin binding protein C, slow type
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RBM47 RNA binding motif protein 47
RGS10 regulator of G-protein signaling 10
RNMT RNA (guanine-7-) methyltransferase
SPTBN1 spectrin, beta, non-erythrocytic 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNM synemin, intermediate filament protein
TCTA T-cell leukemia translocation altered
TFPI2 tissue factor pathway inhibitor 2
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BEX4 brain expressed, X-linked 4
CDC25A cell division cycle 25A
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CPB1 carboxypeptidase B1 (tissue)
DACH1 dachshund family transcription factor 1
DCN decorin
EIF5 eukaryotic translation initiation factor 5
EREG epiregulin
GCH1 GTP cyclohydrolase 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBB hemoglobin, beta
HOXB2 homeobox B2
HOXB6 homeobox B6
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
JMJD6 jumonji domain containing 6
KLF5 Kruppel-like factor 5 (intestinal)
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
LYST lysosomal trafficking regulator
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
OXTR oxytocin receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRAME preferentially expressed antigen in melanoma
PRPF4 pre-mRNA processing factor 4
RPP38 ribonuclease P/MRP 38kDa subunit
SCGB2A1 secretoglobin, family 2A, member 1
SDC4 syndecan 4
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
TMEM158 transmembrane protein 158 (gene/pseudogene)
WFDC2 WAP four-disulfide core domain 2
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing