BRD-A45498368_WYE-125132_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A45498368_WYE-125132_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
ARID5B AT rich interactive domain 5B (MRF1-like)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL9A3 collagen, type IX, alpha 3
F2R coagulation factor II (thrombin) receptor
GADD45A growth arrest and DNA-damage-inducible, alpha
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPR137B G protein-coupled receptor 137B
KDM3A lysine (K)-specific demethylase 3A
NAV2 neuron navigator 2
PTN pleiotrophin
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SOX4 SRY (sex determining region Y)-box 4
TFPI2 tissue factor pathway inhibitor 2
TNC tenascin C

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
C6ORF62 chromosome 6 open reading frame 62
CD36 CD36 molecule (thrombospondin receptor)
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
FLRT3 fibronectin leucine rich transmembrane protein 3
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
IFI27 interferon, alpha-inducible protein 27
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KIF5B kinesin family member 5B
LAMP5 lysosomal-associated membrane protein family, member 5
LEF1 lymphoid enhancer-binding factor 1
LYZ lysozyme
MAT2A methionine adenosyltransferase II, alpha
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NNMT nicotinamide N-methyltransferase
NOP16 NOP16 nucleolar protein
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PLXNC1 plexin C1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS3 protease, serine, 3
PSCA prostate stem cell antigen
PSPH phosphoserine phosphatase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNAP25 synaptosomal-associated protein, 25kDa
SPAG4 sperm associated antigen 4
SST somatostatin
TMEM47 transmembrane protein 47