BRD-A45498368_WYE-125132_HT29_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

94 genes differentially expressed following the BRD-A45498368_WYE-125132_HT29_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ANKRD36B ankyrin repeat domain 36B
ANXA1 annexin A1
ASPN asporin
ASRGL1 asparaginase like 1
ATP9A ATPase, class II, type 9A
BHLHE41 basic helix-loop-helix family, member e41
C14ORF132 chromosome 14 open reading frame 132
C6ORF62 chromosome 6 open reading frame 62
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK5RAP3 CDK5 regulatory subunit associated protein 3
COLEC12 collectin sub-family member 12
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DUSP6 dual specificity phosphatase 6
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP4 fatty acid binding protein 4, adipocyte
FAM46A family with sequence similarity 46, member A
GALC galactosylceramidase
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GOLGA8A golgin A8 family, member A
GPX4 glutathione peroxidase 4
GSN gelsolin
HLA-E major histocompatibility complex, class I, E
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
JAM3 junctional adhesion molecule 3
KIZ kizuna centrosomal protein
MACF1 microtubule-actin crosslinking factor 1
MAST4 microtubule associated serine/threonine kinase family member 4
MFAP5 microfibrillar associated protein 5
MGLL monoglyceride lipase
MLPH melanophilin
MVP major vault protein
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCK1 NCK adaptor protein 1
NPDC1 neural proliferation, differentiation and control, 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
POSTN periostin, osteoblast specific factor
SOX9 SRY (sex determining region Y)-box 9
SRPX sushi-repeat containing protein, X-linked
STXBP1 syntaxin binding protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TJP2 tight junction protein 2
TMC5 transmembrane channel-like 5
TMSB15A thymosin beta 15a
TPPP3 tubulin polymerization-promoting protein family member 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAT1 vesicle amine transport 1
ZBTB20 zinc finger and BTB domain containing 20
ZFPM2 zinc finger protein, FOG family member 2
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CCNF cyclin F
CDC25A cell division cycle 25A
CLU clusterin
CSTA cystatin A (stefin A)
CYB5A cytochrome b5 type A (microsomal)
DEFB1 defensin, beta 1
F13A1 coagulation factor XIII, A1 polypeptide
FAM129A family with sequence similarity 129, member A
FGFR3 fibroblast growth factor receptor 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IL1R2 interleukin 1 receptor, type II
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
MMP12 matrix metallopeptidase 12
MYCBP MYC binding protein
PDHX pyruvate dehydrogenase complex, component X
PHGDH phosphoglycerate dehydrogenase
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PSAT1 phosphoserine aminotransferase 1
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SC5D sterol-C5-desaturase
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SUB1 SUB1 homolog (S. cerevisiae)
VCAM1 vascular cell adhesion molecule 1