BRD-A45498368_WYE-125132_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-A45498368_WYE-125132_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX2 armadillo repeat containing, X-linked 2
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD44 CD44 molecule (Indian blood group)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CYBA cytochrome b-245, alpha polypeptide
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EGR1 early growth response 1
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FRS2 fibroblast growth factor receptor substrate 2
FZD7 frizzled class receptor 7
GPX3 glutathione peroxidase 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
IGF1R insulin-like growth factor 1 receptor
KLF6 Kruppel-like factor 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
PEG10 paternally expressed 10
PROM1 prominin 1
RNASET2 ribonuclease T2
SOX4 SRY (sex determining region Y)-box 4
STAP1 signal transducing adaptor family member 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TBX2 T-box 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM45A transmembrane protein 45A
TUSC3 tumor suppressor candidate 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
AUTS2 autism susceptibility candidate 2
CA2 carbonic anhydrase II
CCND2 cyclin D2
CDC25A cell division cycle 25A
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CSTA cystatin A (stefin A)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
DDIT4 DNA-damage-inducible transcript 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FHL1 four and a half LIM domains 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GSTA1 glutathione S-transferase alpha 1
HSPA1A heat shock 70kDa protein 1A
HSPG2 heparan sulfate proteoglycan 2
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KRT13 keratin 13, type I
LAMA3 laminin, alpha 3
LDHB lactate dehydrogenase B
LMO2 LIM domain only 2 (rhombotin-like 1)
MPZL2 myelin protein zero-like 2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
NKX3-1 NK3 homeobox 1
PDE4B phosphodiesterase 4B, cAMP-specific
PEX11A peroxisomal biogenesis factor 11 alpha
PI3 peptidase inhibitor 3, skin-derived
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RTN1 reticulon 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN13 tetraspanin 13
VAV3 vav 3 guanine nucleotide exchange factor