BRD-A45498368_WYE-125132_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

113 genes differentially expressed following the BRD-A45498368_WYE-125132_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AMOTL2 angiomotin like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
CADM1 cell adhesion molecule 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L2 chitinase 3-like 2
CHIC2 cysteine-rich hydrophobic domain 2
CTGF connective tissue growth factor
CXCL3 chemokine (C-X-C motif) ligand 3
DAPK1 death-associated protein kinase 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
FOXG1 forkhead box G1
FXYD2 FXYD domain containing ion transport regulator 2
GADD45B growth arrest and DNA-damage-inducible, beta
GATA3 GATA binding protein 3
GEM GTP binding protein overexpressed in skeletal muscle
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H2AC histone cluster 1, H2ac
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IRS1 insulin receptor substrate 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLF6 Kruppel-like factor 6
KLHL21 kelch-like family member 21
LETMD1 LETM1 domain containing 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAL mal, T-cell differentiation protein
MAP7 microtubule-associated protein 7
MFAP3L microfibrillar-associated protein 3-like
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
POSTN periostin, osteoblast specific factor
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RND3 Rho family GTPase 3
RNF13 ring finger protein 13
SLC38A2 solute carrier family 38, member 2
STC2 stanniocalcin 2
STX1A syntaxin 1A (brain)
STX7 syntaxin 7
TBX2 T-box 2
TCTA T-cell leukemia translocation altered
TFPI2 tissue factor pathway inhibitor 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRPS1 trichorhinophalangeal syndrome I
TSC22D3 TSC22 domain family, member 3
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
AXL AXL receptor tyrosine kinase
BCHE butyrylcholinesterase
CCL19 chemokine (C-C motif) ligand 19
CCND1 cyclin D1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CSTA cystatin A (stefin A)
CTSZ cathepsin Z
DDIT4 DNA-damage-inducible transcript 4
DPYSL3 dihydropyrimidinase-like 3
EFS embryonal Fyn-associated substrate
EPHA3 EPH receptor A3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FASTKD5 FAST kinase domains 5
GSTA1 glutathione S-transferase alpha 1
KRT13 keratin 13, type I
KRT5 keratin 5, type II
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
MAOA monoamine oxidase A
MAP1B microtubule-associated protein 1B
MGST2 microsomal glutathione S-transferase 2
MXRA7 matrix-remodelling associated 7
NEFH neurofilament, heavy polypeptide
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NKX3-1 NK3 homeobox 1
NMU neuromedin U
NOP16 NOP16 nucleolar protein
NRIP1 nuclear receptor interacting protein 1
NXN nucleoredoxin
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRELP proline/arginine-rich end leucine-rich repeat protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBP1 retinol binding protein 1, cellular
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SELENBP1 selenium binding protein 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TF transferrin
THAP11 THAP domain containing 11
TIGAR TP53 induced glycolysis regulatory phosphatase