BRD-A45498368_WYE-125132_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

160 genes differentially expressed following the BRD-A45498368_WYE-125132_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ANXA3 annexin A3
ATP9A ATPase, class II, type 9A
BMP4 bone morphogenetic protein 4
C6ORF48 chromosome 6 open reading frame 48
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
COL8A2 collagen, type VIII, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
DENND2D DENN/MADD domain containing 2D
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
EDN1 endothelin 1
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF4B eukaryotic translation initiation factor 4B
EPCAM epithelial cell adhesion molecule
ETHE1 ethylmalonic encephalopathy 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAR2 fatty acyl CoA reductase 2
FOXG1 forkhead box G1
GLTSCR2 glioma tumor suppressor candidate region gene 2
GOLGA8H golgin A8 family, member H
HAUS4 HAUS augmin-like complex, subunit 4
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IRS2 insulin receptor substrate 2
ITGB4 integrin, beta 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT81 keratin 81, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LETMD1 LETM1 domain containing 1
LTA4H leukotriene A4 hydrolase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NOTCH1 notch 1
OSBPL1A oxysterol binding protein-like 1A
PADI2 peptidyl arginine deiminase, type II
PECR peroxisomal trans-2-enoyl-CoA reductase
PILRB paired immunoglobin-like type 2 receptor beta
PLAU plasminogen activator, urokinase
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKCD protein kinase C, delta
RAP1GAP2 RAP1 GTPase activating protein 2
REG1A regenerating islet-derived 1 alpha
RGS5 regulator of G-protein signaling 5
SFRP4 secreted frizzled-related protein 4
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SQRDL sulfide quinone reductase-like (yeast)
SULF1 sulfatase 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMC5 transmembrane channel-like 5
TOX thymocyte selection-associated high mobility group box
TRD T cell receptor delta locus
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACAT2 acetyl-CoA acetyltransferase 2
ADGRG1 adhesion G protein-coupled receptor G1
ADI1 acireductone dioxygenase 1
AK4 adenylate kinase 4
AKR1C3 aldo-keto reductase family 1, member C3
ALB albumin
ALDOC aldolase C, fructose-bisphosphate
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
APOA2 apolipoprotein A-II
AQP3 aquaporin 3 (Gill blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCHE butyrylcholinesterase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CLN5 ceroid-lipofuscinosis, neuronal 5
CLU clusterin
CPA3 carboxypeptidase A3 (mast cell)
CTSC cathepsin C
CTSZ cathepsin Z
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EMP3 epithelial membrane protein 3
ENO1 enolase 1, (alpha)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM162A family with sequence similarity 162, member A
FKBP14 FK506 binding protein 14, 22 kDa
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GARS glycyl-tRNA synthetase
GATA2 GATA binding protein 2
GSTM3 glutathione S-transferase mu 3 (brain)
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB8 heat shock 22kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KCNK3 potassium channel, two pore domain subfamily K, member 3
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KRT10 keratin 10, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LDLR low density lipoprotein receptor
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LY6D lymphocyte antigen 6 complex, locus D
MAGEA3 melanoma antigen family A3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
METTL7A methyltransferase like 7A
MINA MYC induced nuclear antigen
MSMO1 methylsterol monooxygenase 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PSAT1 phosphoserine aminotransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPN2 ribophorin II
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SORD sorbitol dehydrogenase
SPAG4 sperm associated antigen 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SQLE squalene epoxidase
SRPRB signal recognition particle receptor, B subunit
STC2 stanniocalcin 2
SUB1 SUB1 homolog (S. cerevisiae)
TARS threonyl-tRNA synthetase
TFRC transferrin receptor
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
YARS tyrosyl-tRNA synthetase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta