BRD-A44780397_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-A44780397_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACADVL acyl-CoA dehydrogenase, very long chain
ADIRF adipogenesis regulatory factor
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCL6 B-cell CLL/lymphoma 6
COL3A1 collagen, type III, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
DACH1 dachshund family transcription factor 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
ELANE elastase, neutrophil expressed
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
GUSBP11 glucuronidase, beta pseudogene 11
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IL1R1 interleukin 1 receptor, type I
JAG1 jagged 1
LMOD1 leiomodin 1 (smooth muscle)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MPO myeloperoxidase
MVP major vault protein
MYH11 myosin, heavy chain 11, smooth muscle
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PSAT1 phosphoserine aminotransferase 1
RFTN1 raftlin, lipid raft linker 1
RTN2 reticulon 2
SH3YL1 SH3 and SYLF domain containing 1
SPRY2 sprouty homolog 2 (Drosophila)
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
TLE4 transducin-like enhancer of split 4
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
BAG2 BCL2-associated athanogene 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KYNU kynureninase
MARCKS myristoylated alanine-rich protein kinase C substrate
PNMA1 paraneoplastic Ma antigen 1
PRSS23 protease, serine, 23
RPA3 replication protein A3, 14kDa
TYMS thymidylate synthetase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)