BRD-A43155244_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

155 genes differentially expressed following the BRD-A43155244_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD3 abhydrolase domain containing 3
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANKRD10 ankyrin repeat domain 10
ARC activity-regulated cytoskeleton-associated protein
ARL4C ADP-ribosylation factor-like 4C
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BTG3 BTG family, member 3
CADM1 cell adhesion molecule 1
CBR3 carbonyl reductase 3
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL1A2 collagen, type I, alpha 2
COL6A2 collagen, type VI, alpha 2
CSRP2 cysteine and glycine-rich protein 2
CYB5R1 cytochrome b5 reductase 1
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ECM1 extracellular matrix protein 1
EIF1 eukaryotic translation initiation factor 1
EIF5A eukaryotic translation initiation factor 5A
ELOVL5 ELOVL fatty acid elongase 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FHL2 four and a half LIM domains 2
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GAL galanin/GMAP prepropeptide
GLUL glutamate-ammonia ligase
GPM6B glycoprotein M6B
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFRD1 interferon-related developmental regulator 1
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCL1 myeloid cell leukemia 1
MEF2C myocyte enhancer factor 2C
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
NBPF10 neuroblastoma breakpoint family, member 10
NQO1 NAD(P)H dehydrogenase, quinone 1
NXF1 nuclear RNA export factor 1
ORM1 orosomucoid 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLIN2 perilipin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POPDC3 popeye domain containing 3
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RHOB ras homolog family member B
RRAD Ras-related associated with diabetes
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A1 secretoglobin, family 2A, member 1
SERINC5 serine incorporator 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOCS2 suppressor of cytokine signaling 2
SQSTM1 sequestosome 1
TRIB1 tribbles pseudokinase 1
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
VSIG4 V-set and immunoglobulin domain containing 4
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
B3GNT1
BMP4 bone morphogenetic protein 4
CANT1 calcium activated nucleotidase 1
CDC25B cell division cycle 25B
COX17 COX17 cytochrome c oxidase copper chaperone
CTSC cathepsin C
CTSH cathepsin H
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DKC1 dyskeratosis congenita 1, dyskerin
GBP1 guanylate binding protein 1, interferon-inducible
GMDS GDP-mannose 4,6-dehydratase
GOLGA8A golgin A8 family, member A
IER3 immediate early response 3
KRT20 keratin 20, type I
MGLL monoglyceride lipase
MRPS16 mitochondrial ribosomal protein S16
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
NME4 NME/NM23 nucleoside diphosphate kinase 4
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PLK1 polo-like kinase 1
PPAP2C phosphatidic acid phosphatase type 2C
PPARG peroxisome proliferator-activated receptor gamma
PRSS2 protease, serine, 2 (trypsin 2)
RELN reelin
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TESC tescalcin
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN8 tetraspanin 8
ZNF185 zinc finger protein 185 (LIM domain)