BRD-A43087975_5540735_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A43087975_5540735_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADD3 adducin 3 (gamma)
AURKB aurora kinase B
C3 complement component 3
CD8A CD8a molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
CPE carboxypeptidase E
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FXYD6 FXYD domain containing ion transport regulator 6
GRB7 growth factor receptor-bound protein 7
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUSBP11 glucuronidase, beta pseudogene 11
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KIZ kizuna centrosomal protein
KRT19 keratin 19, type I
KRT23 keratin 23, type I
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP9 matrix metallopeptidase 9
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SDC1 syndecan 1
SHB Src homology 2 domain containing adaptor protein B
SNX7 sorting nexin 7
SULF1 sulfatase 1
TCEA2 transcription elongation factor A (SII), 2
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VCAN versican
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
BASP1 brain abundant, membrane attached signal protein 1
CDK19 cyclin-dependent kinase 19
CHL1 cell adhesion molecule L1-like
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
GAS1 growth arrest-specific 1
HOXA10 homeobox A10
MAPK6 mitogen-activated protein kinase 6
MFF mitochondrial fission factor
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGES prostaglandin E synthase
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SET SET nuclear proto-oncogene
SH3BP4 SH3-domain binding protein 4
SLCO1B3 solute carrier organic anion transporter family, member 1B3
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8