BRD-A42737819_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-A42737819_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANXA5 annexin A5
ARG2 arginase 2
BTG1 B-cell translocation gene 1, anti-proliferative
CCND2 cyclin D2
CD14 CD14 molecule
CKAP4 cytoskeleton-associated protein 4
COCH cochlin
CXCL8 chemokine (C-X-C motif) ligand 8
DEGS1 delta(4)-desaturase, sphingolipid 1
DLK1 delta-like 1 homolog (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
DUSP10 dual specificity phosphatase 10
FADS1 fatty acid desaturase 1
FCGBP Fc fragment of IgG binding protein
FCN1 ficolin (collagen/fibrinogen domain containing) 1
GOLGA8A golgin A8 family, member A
GPATCH8 G patch domain containing 8
GPX2 glutathione peroxidase 2
ITM2A integral membrane protein 2A
KDM3A lysine (K)-specific demethylase 3A
MATN2 matrilin 2
MEX3C mex-3 RNA binding family member C
PCDH9 protocadherin 9
PEG3 paternally expressed 3
PIP prolactin-induced protein
SPON2 spondin 2, extracellular matrix protein
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM29 tripartite motif containing 29
TSPO translocator protein (18kDa)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZIC1 Zic family member 1

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ATP9A ATPase, class II, type 9A
CA2 carbonic anhydrase II
CCND1 cyclin D1
CNOT4 CCR4-NOT transcription complex, subunit 4
COL3A1 collagen, type III, alpha 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
FOS FBJ murine osteosarcoma viral oncogene homolog
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HMOX2 heme oxygenase 2
HNMT histamine N-methyltransferase
HOXB2 homeobox B2
KAZN kazrin, periplakin interacting protein
KRT6B keratin 6B, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LMO3 LIM domain only 3 (rhombotin-like 2)
MPO myeloperoxidase
NPR3 natriuretic peptide receptor 3
PXDN peroxidasin
RFTN1 raftlin, lipid raft linker 1
RGS4 regulator of G-protein signaling 4
S100A2 S100 calcium binding protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TNS3 tensin 3
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
WNT5A wingless-type MMTV integration site family, member 5A