BRD-A41692738_TGX-221_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A41692738_TGX-221_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
BAMBI BMP and activin membrane-bound inhibitor
BLNK B-cell linker
CCNG2 cyclin G2
CDC25B cell division cycle 25B
DCN decorin
DEFB1 defensin, beta 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EMX2 empty spiracles homeobox 2
FGFR2 fibroblast growth factor receptor 2
GPX3 glutathione peroxidase 3
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB4A RAB4A, member RAS oncogene family
RNASE4 ribonuclease, RNase A family, 4
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AREG amphiregulin
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD3D CD3d molecule, delta (CD3-TCR complex)
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
GAL galanin/GMAP prepropeptide
HBEGF heparin-binding EGF-like growth factor
HMGA2 high mobility group AT-hook 2
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL13RA2 interleukin 13 receptor, alpha 2
JUN jun proto-oncogene
LDHB lactate dehydrogenase B
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MALL mal, T-cell differentiation protein-like
MAP7 microtubule-associated protein 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NUP98 nucleoporin 98kDa
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
POPDC3 popeye domain containing 3
PRKCH protein kinase C, eta
RBM34 RNA binding motif protein 34
RGS4 regulator of G-protein signaling 4
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
STAT1 signal transducer and activator of transcription 1, 91kDa
STC2 stanniocalcin 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLR4 toll-like receptor 4
TSPAN8 tetraspanin 8
TUBB6 tubulin, beta 6 class V
XIST X inactive specific transcript (non-protein coding)
XK X-linked Kx blood group