BRD-A41692738_TGX-221_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A41692738_TGX-221_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AOX1 aldehyde oxidase 1
BAMBI BMP and activin membrane-bound inhibitor
BHMT betaine--homocysteine S-methyltransferase
CADM1 cell adhesion molecule 1
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHI3L2 chitinase 3-like 2
CREB3L2 cAMP responsive element binding protein 3-like 2
EAPP E2F-associated phosphoprotein
EFNA1 ephrin-A1
FAM107A family with sequence similarity 107, member A
FBN2 fibrillin 2
FCGBP Fc fragment of IgG binding protein
FGG fibrinogen gamma chain
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
HILPDA hypoxia inducible lipid droplet-associated
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
KIAA0355 KIAA0355
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MMP9 matrix metallopeptidase 9
MTSS1 metastasis suppressor 1
PEG10 paternally expressed 10
RPS4Y1 ribosomal protein S4, Y-linked 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SQLE squalene epoxidase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STOM stomatin
TSPAN6 tetraspanin 6
VSNL1 visinin-like 1
WNK1 WNK lysine deficient protein kinase 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BST2 bone marrow stromal cell antigen 2
BZW2 basic leucine zipper and W2 domains 2
CBR3 carbonyl reductase 3
COL6A1 collagen, type VI, alpha 1
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DUSP4 dual specificity phosphatase 4
EGR2 early growth response 2
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER3 immediate early response 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JCHAIN joining chain of multimeric IgA and IgM
MMP7 matrix metallopeptidase 7
NAV3 neuron navigator 3
NELL2 NEL-like 2 (chicken)
NRIP1 nuclear receptor interacting protein 1
PDHX pyruvate dehydrogenase complex, component X
PHLDA2 pleckstrin homology-like domain, family A, member 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTX3 pentraxin 3, long
SCGB2A2 secretoglobin, family 2A, member 2
SRGN serglycin
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VIM vimentin