BRD-A41519720_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-A41519720_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
DDIT4 DNA-damage-inducible transcript 4
FTH1 ferritin, heavy polypeptide 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
LEPR leptin receptor
LTF lactotransferrin
MB myoglobin
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
IGFBP5 insulin-like growth factor binding protein 5
IL7R interleukin 7 receptor
KIF14 kinesin family member 14
SMS spermine synthase
SPINK1 serine peptidase inhibitor, Kazal type 1