BRD-A41519720_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

64 genes differentially expressed following the BRD-A41519720_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
AGR2 anterior gradient 2
ANO1 anoctamin 1, calcium activated chloride channel
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
CBX1 chromobox homolog 1
CD163 CD163 molecule
CHN2 chimerin 2
COL11A1 collagen, type XI, alpha 1
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
CRIP1 cysteine-rich protein 1 (intestinal)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
F13A1 coagulation factor XIII, A1 polypeptide
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXB6 homeobox B6
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LDLR low density lipoprotein receptor
MAP7 microtubule-associated protein 7
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUCB2 nucleobindin 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFD platelet derived growth factor D
PPIB peptidylprolyl isomerase B (cyclophilin B)
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC24D SEC24 family member D
SERINC5 serine incorporator 5
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC43A3 solute carrier family 43, member 3
SPON1 spondin 1, extracellular matrix protein
SQLE squalene epoxidase
STXBP6 syntaxin binding protein 6 (amisyn)
THBS2 thrombospondin 2
TWIST1 twist family bHLH transcription factor 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
CCND2 cyclin D2
CCNF cyclin F
CLEC2B C-type lectin domain family 2, member B
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
ITGA6 integrin, alpha 6
KAZN kazrin, periplakin interacting protein
LAPTM4B lysosomal protein transmembrane 4 beta
RNF167 ring finger protein 167
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
TFPI2 tissue factor pathway inhibitor 2