BRD-A41301928_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-A41301928_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
CD48 CD48 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGL2 fibrinogen-like 2
FRY furry homolog (Drosophila)
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRB7 growth factor receptor-bound protein 7
GUSBP11 glucuronidase, beta pseudogene 11
HOPX HOP homeobox
IFI44L interferon-induced protein 44-like
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
LPAR6 lysophosphatidic acid receptor 6
LYPD3 LY6/PLAUR domain containing 3
MKNK1 MAP kinase interacting serine/threonine kinase 1
MX1 MX dynamin-like GTPase 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SRGN serglycin
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPCAM epithelial cell adhesion molecule
HSPB8 heat shock 22kDa protein 8
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NOLC1 nucleolar and coiled-body phosphoprotein 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SORD sorbitol dehydrogenase