BRD-A41250306_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

12 genes differentially expressed following the BRD-A41250306_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD40 CD40 molecule, TNF receptor superfamily member 5
DPYD dihydropyrimidine dehydrogenase
IKZF1 IKAROS family zinc finger 1 (Ikaros)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PSPH phosphoserine phosphatase

decreased expression

Symbol Name
ASCL1 achaete-scute family bHLH transcription factor 1
GSN gelsolin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
QPCT glutaminyl-peptide cyclotransferase
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2