BRD-A39996500_radicicol_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

110 genes differentially expressed following the BRD-A39996500_radicicol_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ANXA2 annexin A2
BAG3 BCL2-associated athanogene 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
FABP4 fatty acid binding protein 4, adipocyte
FN1 fibronectin 1
GPM6B glycoprotein M6B
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IFI27 interferon, alpha-inducible protein 27
IGFBP4 insulin-like growth factor binding protein 4
IL6ST interleukin 6 signal transducer
KIAA0355 KIAA0355
KRT18 keratin 18, type I
KRT5 keratin 5, type II
LAPTM4B lysosomal protein transmembrane 4 beta
MTUS1 microtubule associated tumor suppressor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PON2 paraoxonase 2
PSPH phosphoserine phosphatase
RHOB ras homolog family member B
SFN stratifin
SORBS3 sorbin and SH3 domain containing 3
STXBP2 syntaxin binding protein 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP3 TIMP metallopeptidase inhibitor 3

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ALDOB aldolase B, fructose-bisphosphate
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C7 complement component 7
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CD52 CD52 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC2 chloride intracellular channel 2
COL14A1 collagen, type XIV, alpha 1
CPE carboxypeptidase E
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEPTOR DEP domain containing MTOR-interacting protein
DPT dermatopontin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPN2 epsin 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GATA2 GATA binding protein 2
GJA1 gap junction protein, alpha 1, 43kDa
GREM1 gremlin 1, DAN family BMP antagonist
GSTP1 glutathione S-transferase pi 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JCHAIN joining chain of multimeric IgA and IgM
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMP3 lysosomal-associated membrane protein 3
LCN2 lipocalin 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMO2 LIM domain only 2 (rhombotin-like 1)
LTF lactotransferrin
MDK midkine (neurite growth-promoting factor 2)
MEIS2 Meis homeobox 2
MN1 meningioma (disrupted in balanced translocation) 1
MYH11 myosin, heavy chain 11, smooth muscle
NCAM1 neural cell adhesion molecule 1
NCF2 neutrophil cytosolic factor 2
NMU neuromedin U
NRN1 neuritin 1
OLFM4 olfactomedin 4
OSBPL10 oxysterol binding protein-like 10
PDZRN3 PDZ domain containing ring finger 3
PEG3 paternally expressed 3
PLAT plasminogen activator, tissue
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
REEP1 receptor accessory protein 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN1 reticulon 1
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SATB1 SATB homeobox 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX11 SRY (sex determining region Y)-box 11
SPP1 secreted phosphoprotein 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TMSB15A thymosin beta 15a
ZDHHC11 zinc finger, DHHC-type containing 11