BRD-A39996500_radicicol_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

128 genes differentially expressed following the BRD-A39996500_radicicol_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOE apolipoprotein E
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BAG3 BCL2-associated athanogene 3
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CAB39 calcium binding protein 39
CCL2 chemokine (C-C motif) ligand 2
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CTGF connective tissue growth factor
CTSH cathepsin H
DAPK1 death-associated protein kinase 1
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DIO2 deiodinase, iodothyronine, type II
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP22 dual specificity phosphatase 22
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
HBB hemoglobin, beta
HIST1H2BG histone cluster 1, H2bg
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
KLK11 kallikrein-related peptidase 11
MB myoglobin
MGP matrix Gla protein
MUC16 mucin 16, cell surface associated
MYBPC1 myosin binding protein C, slow type
MYO6 myosin VI
NEFH neurofilament, heavy polypeptide
NLGN4X neuroligin 4, X-linked
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEG3 paternally expressed 3
PHGDH phosphoglycerate dehydrogenase
PLAC8 placenta-specific 8
PLK2 polo-like kinase 2
POSTN periostin, osteoblast specific factor
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TBX2 T-box 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMSB15A thymosin beta 15a
TNNC1 troponin C type 1 (slow)
TSPAN8 tetraspanin 8
WFDC2 WAP four-disulfide core domain 2
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BLNK B-cell linker
BMP2 bone morphogenetic protein 2
CADM1 cell adhesion molecule 1
CCL19 chemokine (C-C motif) ligand 19
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CP ceruloplasmin (ferroxidase)
CPVL carboxypeptidase, vitellogenic-like
CREB1 cAMP responsive element binding protein 1
EPHA3 EPH receptor A3
EREG epiregulin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FGFR3 fibroblast growth factor receptor 3
FOXC1 forkhead box C1
FST follistatin
GAGE3 G antigen 3
GBP1 guanylate binding protein 1, interferon-inducible
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPNMB glycoprotein (transmembrane) nmb
HOXA10 homeobox A10
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IGLL1 immunoglobulin lambda-like polypeptide 1
IL13RA2 interleukin 13 receptor, alpha 2
IRF8 interferon regulatory factor 8
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT15 keratin 15, type I
LAP3 leucine aminopeptidase 3
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
MET MET proto-oncogene, receptor tyrosine kinase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
NUSAP1 nucleolar and spindle associated protein 1
PCP4 Purkinje cell protein 4
PCSK1 proprotein convertase subtilisin/kexin type 1
PERP PERP, TP53 apoptosis effector
PLCB4 phospholipase C, beta 4
PLIN1 perilipin 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RND3 Rho family GTPase 3
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SATB1 SATB homeobox 1
SESN1 sestrin 1
SLC38A2 solute carrier family 38, member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPP1 secreted phosphoprotein 1
SRSF6 serine/arginine-rich splicing factor 6
TCF4 transcription factor 4
TLR4 toll-like receptor 4
TRAC T cell receptor alpha constant
TRD T cell receptor delta locus
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1
WARS tryptophanyl-tRNA synthetase
ZFP36L2 ZFP36 ring finger protein-like 2