BRD-A39996500_radicicol_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-A39996500_radicicol_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACBD3 acyl-CoA binding domain containing 3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BAG3 BCL2-associated athanogene 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTG2 BTG family, member 2
C3ORF52 chromosome 3 open reading frame 52
CCR2 chemokine (C-C motif) receptor 2
CD163 CD163 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CKAP4 cytoskeleton-associated protein 4
CREB3L2 cAMP responsive element binding protein 3-like 2
CTSZ cathepsin Z
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FAM46C family with sequence similarity 46, member C
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXF1 forkhead box F1
GATA3 GATA binding protein 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
JMJD6 jumonji domain containing 6
KCTD12 potassium channel tetramerization domain containing 12
KRT19 keratin 19, type I
KRT7 keratin 7, type II
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
OAT ornithine aminotransferase
PERP PERP, TP53 apoptosis effector
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RAD9A RAD9 homolog A (S. pombe)
RNASE4 ribonuclease, RNase A family, 4
SCRG1 stimulator of chondrogenesis 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SRGN serglycin

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CDK4 cyclin-dependent kinase 4
CTSH cathepsin H
DEPTOR DEP domain containing MTOR-interacting protein
DLK1 delta-like 1 homolog (Drosophila)
ELOVL5 ELOVL fatty acid elongase 5
FADS1 fatty acid desaturase 1
FSTL1 follistatin-like 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GANAB glucosidase, alpha; neutral AB
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HACD3 3-hydroxyacyl-CoA dehydratase 3
HES1 hes family bHLH transcription factor 1
LAMP1 lysosomal-associated membrane protein 1
MARCKSL1 MARCKS-like 1
MYBPC1 myosin binding protein C, slow type
NDN necdin, melanoma antigen (MAGE) family member
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPY1R neuropeptide Y receptor Y1
NTS neurotensin
PLAGL1 pleiomorphic adenoma gene-like 1
PRPF19 pre-mRNA processing factor 19
PUF60 poly-U binding splicing factor 60KDa
RBP1 retinol binding protein 1, cellular
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
TFF3 trefoil factor 3 (intestinal)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAN versican