BRD-A39996500_radicicol_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-A39996500_radicicol_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP1 aquaporin 1 (Colton blood group)
ASCL1 achaete-scute family bHLH transcription factor 1
BAG3 BCL2-associated athanogene 3
BEX1 brain expressed, X-linked 1
C10ORF10 chromosome 10 open reading frame 10
CHN1 chimerin 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CRIP1 cysteine-rich protein 1 (intestinal)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GNAS GNAS complex locus
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
KLF4 Kruppel-like factor 4 (gut)
KRT7 keratin 7, type II
LIMCH1 LIM and calponin homology domains 1
LXN latexin
LYZ lysozyme
MAN2B1 mannosidase, alpha, class 2B, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MUC7 mucin 7, secreted
NEFL neurofilament, light polypeptide
NMRK1 nicotinamide riboside kinase 1
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SNAP25 synaptosomal-associated protein, 25kDa
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
THBS1 thrombospondin 1

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CAB39 calcium binding protein 39
FST follistatin
FZD7 frizzled class receptor 7
GPNMB glycoprotein (transmembrane) nmb
H1F0 H1 histone family, member 0
HACD3 3-hydroxyacyl-CoA dehydratase 3
KRT6B keratin 6B, type II
MAP7 microtubule-associated protein 7
MMP1 matrix metallopeptidase 1
PTPRK protein tyrosine phosphatase, receptor type, K
PXDN peroxidasin
SEPP1 selenoprotein P, plasma, 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SPON2 spondin 2, extracellular matrix protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)