BRD-A39996500_radicicol_HME1_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-A39996500_radicicol_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CPM carboxypeptidase M
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF5A eukaryotic translation initiation factor 5A
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JMJD6 jumonji domain containing 6
LIMCH1 LIM and calponin homology domains 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
APOLD1 apolipoprotein L domain containing 1
APP amyloid beta (A4) precursor protein
AREG amphiregulin
CA12 carbonic anhydrase XII
CCNB1 cyclin B1
CCND2 cyclin D2
FAS Fas cell surface death receptor
GDF15 growth differentiation factor 15
HP haptoglobin
HRSP12 heat-responsive protein 12
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
JADE2 jade family PHD finger 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KYNU kynureninase
MAOA monoamine oxidase A
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PODXL podocalyxin-like
REG1A regenerating islet-derived 1 alpha
RHOBTB3 Rho-related BTB domain containing 3
S100A14 S100 calcium binding protein A14
SGK1 serum/glucocorticoid regulated kinase 1
STC1 stanniocalcin 1
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
ZDHHC11 zinc finger, DHHC-type containing 11