BRD-A39996500_radicicol_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-A39996500_radicicol_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
C6ORF48 chromosome 6 open reading frame 48
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FTH1 ferritin, heavy polypeptide 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LDHB lactate dehydrogenase B
MALL mal, T-cell differentiation protein-like
NKX2-1 NK2 homeobox 1
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
SFTPB surfactant protein B
TMED3 transmembrane emp24 protein transport domain containing 3
TTC39A tetratricopeptide repeat domain 39A
TTN titin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
ADRB2 adrenoceptor beta 2, surface
AEBP1 AE binding protein 1
AK4 adenylate kinase 4
AKAP12 A kinase (PRKA) anchor protein 12
ASPN asporin
C1QA complement component 1, q subcomponent, A chain
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CECR1 cat eye syndrome chromosome region, candidate 1
CLC Charcot-Leyden crystal galectin
CST7 cystatin F (leukocystatin)
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLNA filamin A, alpha
GPM6B glycoprotein M6B
GREM1 gremlin 1, DAN family BMP antagonist
H1F0 H1 histone family, member 0
HOXB2 homeobox B2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IL2RG interleukin 2 receptor, gamma
IL32 interleukin 32
JCHAIN joining chain of multimeric IgA and IgM
LYZ lysozyme
MAMLD1 mastermind-like domain containing 1
MCL1 myeloid cell leukemia 1
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MXRA7 matrix-remodelling associated 7
NR2F1 nuclear receptor subfamily 2, group F, member 1
OLFM4 olfactomedin 4
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC2 syndecan 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOX9 SRY (sex determining region Y)-box 9
TAGLN transgelin
THBS1 thrombospondin 1
VSNL1 visinin-like 1
ZFP36L2 ZFP36 ring finger protein-like 2