BRD-A38898897_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A38898897_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCL6 B-cell CLL/lymphoma 6
BHLHE41 basic helix-loop-helix family, member e41
CCR7 chemokine (C-C motif) receptor 7
CYTL1 cytokine-like 1
EGR2 early growth response 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHA3 EPH receptor A3
FAM46A family with sequence similarity 46, member A
GAS1 growth arrest-specific 1
GRB10 growth factor receptor-bound protein 10
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRS1 insulin receptor substrate 1
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
KRT13 keratin 13, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LY75 lymphocyte antigen 75
NR4A3 nuclear receptor subfamily 4, group A, member 3
PCP4 Purkinje cell protein 4
RBPMS RNA binding protein with multiple splicing
RPL37A ribosomal protein L37a
SAMD9 sterile alpha motif domain containing 9
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF4 transmembrane 4 L six family member 4

decreased expression

Symbol Name
ADM adrenomedullin
BMP4 bone morphogenetic protein 4
C6ORF62 chromosome 6 open reading frame 62
CCDC86 coiled-coil domain containing 86
CLIC4 chloride intracellular channel 4
CXCL14 chemokine (C-X-C motif) ligand 14
EGLN3 egl-9 family hypoxia-inducible factor 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FOLR1 folate receptor 1 (adult)
GATA3 GATA binding protein 3
GCH1 GTP cyclohydrolase 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KLK5 kallikrein-related peptidase 5
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LGALS1 lectin, galactoside-binding, soluble, 1
LPAR6 lysophosphatidic acid receptor 6
MAP7 microtubule-associated protein 7
MEF2C myocyte enhancer factor 2C
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
POLR1D polymerase (RNA) I polypeptide D, 16kDa
RHOH ras homolog family member H
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RND3 Rho family GTPase 3
TGFBI transforming growth factor, beta-induced, 68kDa
TRIB2 tribbles pseudokinase 2
ZNF586 zinc finger protein 586