BRD-A37704979_SB-203580_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-A37704979_SB-203580_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD3 acyl-CoA binding domain containing 3
ADIRF adipogenesis regulatory factor
ATF3 activating transcription factor 3
BPHL biphenyl hydrolase-like (serine hydrolase)
CCNA1 cyclin A1
CP ceruloplasmin (ferroxidase)
CRYAB crystallin, alpha B
DAPK1 death-associated protein kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL2 dihydropyrimidinase-like 2
DSG2 desmoglein 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
KRT23 keratin 23, type I
MGP matrix Gla protein
MICALL1 MICAL-like 1
MT1X metallothionein 1X
MX1 MX dynamin-like GTPase 1
MXRA7 matrix-remodelling associated 7
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
PDGFD platelet derived growth factor D
PLA2G16 phospholipase A2, group XVI
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SOCS2 suppressor of cytokine signaling 2
SPTBN1 spectrin, beta, non-erythrocytic 1
TIMP2 TIMP metallopeptidase inhibitor 2
TUBB2A tubulin, beta 2A class IIa
WT1 Wilms tumor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AZU1 azurocidin 1
BAX BCL2-associated X protein
BSG basigin (Ok blood group)
CA12 carbonic anhydrase XII
CAMP cathelicidin antimicrobial peptide
CD24 CD24 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CKAP4 cytoskeleton-associated protein 4
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL5 chemokine (C-X-C motif) ligand 5
DEFA4 defensin, alpha 4, corticostatin
DEPTOR DEP domain containing MTOR-interacting protein
ERBB4 erb-b2 receptor tyrosine kinase 4
FLRT2 fibronectin leucine rich transmembrane protein 2
G6PD glucose-6-phosphate dehydrogenase
GRWD1 glutamate-rich WD repeat containing 1
HEATR1 HEAT repeat containing 1
HIST1H2BG histone cluster 1, H2bg
HP haptoglobin
IFRD2 interferon-related developmental regulator 2
IL1R2 interleukin 1 receptor, type II
ISOC1 isochorismatase domain containing 1
KLK6 kallikrein-related peptidase 6
KYNU kynureninase
LCN2 lipocalin 2
MLPH melanophilin
MRPS2 mitochondrial ribosomal protein S2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEBL nebulette
NRCAM neuronal cell adhesion molecule
NSDHL NAD(P) dependent steroid dehydrogenase-like
OLFM4 olfactomedin 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SECISBP2L SECIS binding protein 2-like
SORD sorbitol dehydrogenase
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SQSTM1 sequestosome 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)