BRD-A37704979_SB-203580_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-A37704979_SB-203580_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATF3 activating transcription factor 3
CD93 CD93 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
CLIC3 chloride intracellular channel 3
CLNS1A chloride channel, nucleotide-sensitive, 1A
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL11A1 collagen, type XI, alpha 1
CRYAB crystallin, alpha B
CXCL10 chemokine (C-X-C motif) ligand 10
DCN decorin
DSP desmoplakin
EED embryonic ectoderm development
ESR1 estrogen receptor 1
FBLN1 fibulin 1
GBP1 guanylate binding protein 1, interferon-inducible
GPNMB glycoprotein (transmembrane) nmb
GRIA2 glutamate receptor, ionotropic, AMPA 2
HIST1H4C histone cluster 1, H4c
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
KLK5 kallikrein-related peptidase 5
KRT23 keratin 23, type I
MFAP5 microfibrillar associated protein 5
MT1M metallothionein 1M
MXRA5 matrix-remodelling associated 5
NUPR1 nuclear protein, transcriptional regulator, 1
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PCP4 Purkinje cell protein 4
PCSK1 proprotein convertase subtilisin/kexin type 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLS3 plastin 3
POSTN periostin, osteoblast specific factor
PPAP2A phosphatidic acid phosphatase type 2A
RCAN1 regulator of calcineurin 1
REXO2 RNA exonuclease 2
SASH1 SAM and SH3 domain containing 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP4 secreted frizzled-related protein 4
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPARCL1 SPARC-like 1 (hevin)
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TMEM126B transmembrane protein 126B
TMEM47 transmembrane protein 47
TPD52L1 tumor protein D52-like 1
XIST X inactive specific transcript (non-protein coding)
ZEB1 zinc finger E-box binding homeobox 1
ZIC1 Zic family member 1

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADORA2B adenosine A2b receptor
ANXA10 annexin A10
BHLHE41 basic helix-loop-helix family, member e41
C7 complement component 7
CD24 CD24 molecule
CD52 CD52 molecule
CLEC11A C-type lectin domain family 11, member A
COL1A2 collagen, type I, alpha 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DLK1 delta-like 1 homolog (Drosophila)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FXYD5 FXYD domain containing ion transport regulator 5
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GFPT2 glutamine-fructose-6-phosphate transaminase 2
JAG1 jagged 1
LRRC17 leucine rich repeat containing 17
MB myoglobin
MYBPC1 myosin binding protein C, slow type
NEB nebulin
NELL2 NEL-like 2 (chicken)
NKX3-1 NK3 homeobox 1
OLFM4 olfactomedin 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PNMA2 paraneoplastic Ma antigen 2
PROM1 prominin 1
S100A9 S100 calcium binding protein A9
SACS sacsin molecular chaperone
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHB Src homology 2 domain containing adaptor protein B
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STEAP3 STEAP family member 3, metalloreductase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMC5 transmembrane channel-like 5
TRH thyrotropin-releasing hormone
TRIB2 tribbles pseudokinase 2
VCAM1 vascular cell adhesion molecule 1
WNT5A wingless-type MMTV integration site family, member 5A