BRD-A37704979_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-A37704979_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AGTR1 angiotensin II receptor, type 1
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CLIC4 chloride intracellular channel 4
CYTL1 cytokine-like 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FABP7 fatty acid binding protein 7, brain
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
KDM5D lysine (K)-specific demethylase 5D
KRT6B keratin 6B, type II
LIF leukemia inhibitory factor
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MSMO1 methylsterol monooxygenase 1
OSBPL3 oxysterol binding protein-like 3
PLAU plasminogen activator, urokinase
S100A6 S100 calcium binding protein A6
SCRN1 secernin 1
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SPATS2L spermatogenesis associated, serine-rich 2-like
SQSTM1 sequestosome 1
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
AQP9 aquaporin 9
AUTS2 autism susceptibility candidate 2
C2CD5 C2 calcium-dependent domain containing 5
C5AR1 complement component 5a receptor 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL7A1 collagen, type VII, alpha 1
CSTA cystatin A (stefin A)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EGFL6 EGF-like-domain, multiple 6
FBP1 fructose-1,6-bisphosphatase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GATA3 GATA binding protein 3
HEATR1 HEAT repeat containing 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NREP neuronal regeneration related protein
NVL nuclear VCP-like
RGS1 regulator of G-protein signaling 1
RNASE6 ribonuclease, RNase A family, k6
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TAGLN2 transgelin 2
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331