BRD-A36630025_-666_HT29_6.0_h_0.35_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

97 genes differentially expressed following the BRD-A36630025_-666_HT29_6.0_h_0.35_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
BEX4 brain expressed, X-linked 4
BTG3 BTG family, member 3
CCNE2 cyclin E2
CDK2 cyclin-dependent kinase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FLG filaggrin
GCH1 GTP cyclohydrolase 1
GUSBP11 glucuronidase, beta pseudogene 11
ITM2A integral membrane protein 2A
MEA1 male-enhanced antigen 1
MZB1 marginal zone B and B1 cell-specific protein
OAT ornithine aminotransferase
PAQR3 progestin and adipoQ receptor family member III
RFK riboflavin kinase
RRAGD Ras-related GTP binding D
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
TMEM251 transmembrane protein 251
UBE2A ubiquitin-conjugating enzyme E2A
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AGR2 anterior gradient 2
AKAP13 A kinase (PRKA) anchor protein 13
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ASCC3 activating signal cointegrator 1 complex subunit 3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
BMP4 bone morphogenetic protein 4
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CTSC cathepsin C
CTSE cathepsin E
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EPS8 epidermal growth factor receptor pathway substrate 8
FAT1 FAT atypical cadherin 1
FGF13 fibroblast growth factor 13
FOLR1 folate receptor 1 (adult)
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX2 glutathione peroxidase 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGA6 integrin, alpha 6
JADE2 jade family PHD finger 2
KAT6B K(lysine) acetyltransferase 6B
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LAMB1 laminin, beta 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LPL lipoprotein lipase
MAP1B microtubule-associated protein 1B
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAST2 microtubule associated serine/threonine kinase 2
MBNL2 muscleblind-like splicing regulator 2
MECOM MDS1 and EVI1 complex locus
MGP matrix Gla protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO10 myosin X
NIPBL Nipped-B homolog (Drosophila)
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
PAM peptidylglycine alpha-amidating monooxygenase
PBX1 pre-B-cell leukemia homeobox 1
PDGFC platelet derived growth factor C
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLK1 polo-like kinase 1
PPARG peroxisome proliferator-activated receptor gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROM1 prominin 1
PSRC1 proline/serine-rich coiled-coil 1
PTK2 protein tyrosine kinase 2
QKI QKI, KH domain containing, RNA binding
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SPTBN1 spectrin, beta, non-erythrocytic 1
TESC tescalcin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
ZMIZ1 zinc finger, MIZ-type containing 1
ZMYND8 zinc finger, MYND-type containing 8