BRD-A36074203_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-A36074203_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BIRC3 baculoviral IAP repeat containing 3
CCDC86 coiled-coil domain containing 86
CCR7 chemokine (C-C motif) receptor 7
COBL cordon-bleu WH2 repeat protein
CYTIP cytohesin 1 interacting protein
DOCK9 dedicator of cytokinesis 9
EHF ets homologous factor
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EXT1 exostosin glycosyltransferase 1
FAM69A family with sequence similarity 69, member A
GDF15 growth differentiation factor 15
GOLGA8B golgin A8 family, member B
HOPX HOP homeobox
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
KIAA1033 KIAA1033
LEF1 lymphoid enhancer-binding factor 1
LIMCH1 LIM and calponin homology domains 1
LXN latexin
MAOA monoamine oxidase A
MET MET proto-oncogene, receptor tyrosine kinase
NAV2 neuron navigator 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5E 5'-nucleotidase, ecto (CD73)
OAT ornithine aminotransferase
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZRN3 PDZ domain containing ring finger 3
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PSD3 pleckstrin and Sec7 domain containing 3
RHOBTB3 Rho-related BTB domain containing 3
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SPRED2 sprouty-related, EVH1 domain containing 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D4 TBC1 domain family, member 4
TGIF1 TGFB-induced factor homeobox 1
TMPRSS2 transmembrane protease, serine 2
TRAF5 TNF receptor-associated factor 5
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
AQP1 aquaporin 1 (Colton blood group)
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CIRBP cold inducible RNA binding protein
CLTB clathrin, light chain B
CRIP2 cysteine-rich protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1 eukaryotic translation initiation factor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADS1 fatty acid desaturase 1
FRZB frizzled-related protein
GPX3 glutathione peroxidase 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFI27 interferon, alpha-inducible protein 27
KDM5D lysine (K)-specific demethylase 5D
MDK midkine (neurite growth-promoting factor 2)
METRN meteorin, glial cell differentiation regulator
MFAP4 microfibrillar-associated protein 4
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PTN pleiotrophin
RBP1 retinol binding protein 1, cellular
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A10 S100 calcium binding protein A10
SCG2 secretogranin II
SEPP1 selenoprotein P, plasma, 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNX7 sorting nexin 7
SPARCL1 SPARC-like 1 (hevin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb