BRD-A35912562_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-A35912562_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CCNB2 cyclin B2
CD58 CD58 molecule
CXCL11 chemokine (C-X-C motif) ligand 11
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBE1 hemoglobin, epsilon 1
HIST1H1C histone cluster 1, H1c
JCHAIN joining chain of multimeric IgA and IgM
KRT81 keratin 81, type II
L1CAM L1 cell adhesion molecule
MPP1 membrane protein, palmitoylated 1, 55kDa
OPTN optineurin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RCAN1 regulator of calcineurin 1

decreased expression

Symbol Name
CXCL8 chemokine (C-X-C motif) ligand 8
GRN granulin
IL13RA2 interleukin 13 receptor, alpha 2
IL6ST interleukin 6 signal transducer
MMP9 matrix metallopeptidase 9
MT1F metallothionein 1F
MT1X metallothionein 1X
PGC progastricsin (pepsinogen C)
SCYL3 SCY1-like 3 (S. cerevisiae)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)