BRD-A35588707_TENIPOSIDE_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

226 genes differentially expressed following the BRD-A35588707_TENIPOSIDE_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AHNAK2 AHNAK nucleoprotein 2
ALOX5 arachidonate 5-lipoxygenase
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
BIRC3 baculoviral IAP repeat containing 3
BLCAP bladder cancer associated protein
BTG2 BTG family, member 2
BTG3 BTG family, member 3
C1ORF116 chromosome 1 open reading frame 116
CA2 carbonic anhydrase II
CAMP cathelicidin antimicrobial peptide
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD24 CD24 molecule
CD52 CD52 molecule
CD69 CD69 molecule
CD83 CD83 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES2 carboxylesterase 2
CKB creatine kinase, brain
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DPT dermatopontin
DUSP14 dual specificity phosphatase 14
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGR1 early growth response 1
EGR2 early growth response 2
FAS Fas cell surface death receptor
FBLN1 fibulin 1
FDXR ferredoxin reductase
FGFR3 fibroblast growth factor receptor 3
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FUCA1 fucosidase, alpha-L- 1, tissue
G0S2 G0/G1 switch 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GCH1 GTP cyclohydrolase 1
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GRN granulin
HBEGF heparin-binding EGF-like growth factor
HLA-B major histocompatibility complex, class I, B
HMOX1 heme oxygenase 1
HSPA4L heat shock 70kDa protein 4-like
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IER5 immediate early response 5
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
INPP1 inositol polyphosphate-1-phosphatase
ITM2A integral membrane protein 2A
JUNB jun B proto-oncogene
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LAMB3 laminin, beta 3
LMNA lamin A/C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MCOLN1 mucolipin 1
NDRG1 N-myc downstream regulated 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NINJ1 ninjurin 1
NKX3-1 NK3 homeobox 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PERP PERP, TP53 apoptosis effector
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIF peptidylprolyl isomerase F
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RALGDS ral guanine nucleotide dissociation stimulator
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBKS ribokinase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RNF19B ring finger protein 19B
RPS27L ribosomal protein S27-like
S100A2 S100 calcium binding protein A2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC4 syndecan 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SESN1 sestrin 1
SFN stratifin
SGPP1 sphingosine-1-phosphate phosphatase 1
SIK1 salt-inducible kinase 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SOD2 superoxide dismutase 2, mitochondrial
ST18 suppression of tumorigenicity 18, zinc finger
TDO2 tryptophan 2,3-dioxygenase
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOB1 transducer of ERBB2, 1
TP63 tumor protein p63
TPD52L1 tumor protein D52-like 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIM22 tripartite motif containing 22
TRIM29 tripartite motif containing 29
TSKU tsukushi, small leucine rich proteoglycan
TUBA4A tubulin, alpha 4a
VEGFA vascular endothelial growth factor A
ZDHHC11 zinc finger, DHHC-type containing 11
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AFF1 AF4/FMR2 family, member 1
AHNAK AHNAK nucleoprotein
AKAP12 A kinase (PRKA) anchor protein 12
ALCAM activated leukocyte cell adhesion molecule
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ARID1A AT rich interactive domain 1A (SWI-like)
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
BEX1 brain expressed, X-linked 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CCNF cyclin F
CDC25B cell division cycle 25B
CDCA3 cell division cycle associated 3
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CFI complement factor I
CP ceruloplasmin (ferroxidase)
CXCL12 chemokine (C-X-C motif) ligand 12
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EPS8 epidermal growth factor receptor pathway substrate 8
FOXJ3 forkhead box J3
FOXO3 forkhead box O3
FZD2 frizzled class receptor 2
GRB10 growth factor receptor-bound protein 10
HMMR hyaluronan-mediated motility receptor (RHAMM)
HN1 hematological and neurological expressed 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HOXA10 homeobox A10
HOXA5 homeobox A5
HOXC6 homeobox C6
IGFBP4 insulin-like growth factor binding protein 4
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
JARID2 jumonji, AT rich interactive domain 2
JCHAIN joining chain of multimeric IgA and IgM
KIAA1551 KIAA1551
LAMP5 lysosomal-associated membrane protein family, member 5
LAPTM4B lysosomal protein transmembrane 4 beta
LARP1 La ribonucleoprotein domain family, member 1
LEF1 lymphoid enhancer-binding factor 1
LMNB1 lamin B1
LPP LIM domain containing preferred translocation partner in lipoma
MBNL1 muscleblind-like splicing regulator 1
MBNL2 muscleblind-like splicing regulator 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO10 myosin X
NR2F2 nuclear receptor subfamily 2, group F, member 2
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
PAM peptidylglycine alpha-amidating monooxygenase
PDS5A PDS5 cohesin associated factor A
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKN2 protein kinase N2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PRC1 protein regulator of cytokinesis 1
PROM1 prominin 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PXDN peroxidasin
QPRT quinolinate phosphoribosyltransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
SEC14L1 SEC14-like 1 (S. cerevisiae)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC35F2 solute carrier family 35, member F2
SMAD3 SMAD family member 3
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMYD2 SET and MYND domain containing 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPE small nuclear ribonucleoprotein polypeptide E
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SYT1 synaptotagmin I
TBC1D4 TBC1 domain family, member 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMPO thymopoietin
TNS1 tensin 1
TNS3 tensin 3
TRAM2 translocation associated membrane protein 2
TYRP1 tyrosinase-related protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCK2 uridine-cytidine kinase 2
XIST X inactive specific transcript (non-protein coding)
XPO7 exportin 7
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZMYND8 zinc finger, MYND-type containing 8