BRD-A35108200_Dexamethasone_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-A35108200_Dexamethasone_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AQP3 aquaporin 3 (Gill blood group)
CCND3 cyclin D3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHIC2 cysteine-rich hydrophobic domain 2
COMP cartilage oligomeric matrix protein
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CYB5A cytochrome b5 type A (microsomal)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FKBP5 FK506 binding protein 5
GADD45B growth arrest and DNA-damage-inducible, beta
IGFBP7 insulin-like growth factor binding protein 7
KLF9 Kruppel-like factor 9
MAOA monoamine oxidase A
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PDE2A phosphodiesterase 2A, cGMP-stimulated
PER1 period circadian clock 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
RAB25 RAB25, member RAS oncogene family
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
ASCL1 achaete-scute family bHLH transcription factor 1
BHLHE41 basic helix-loop-helix family, member e41
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CANX calnexin
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCR7 chemokine (C-C motif) receptor 7
CHRM3 cholinergic receptor, muscarinic 3
CRISP3 cysteine-rich secretory protein 3
DEFB1 defensin, beta 1
GLIPR1 GLI pathogenesis-related 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
LYZ lysozyme
MAGEA12 melanoma antigen family A12
MAGEA6 melanoma antigen family A6
MMP10 matrix metallopeptidase 10
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PROM1 prominin 1
RPL38 ribosomal protein L38
SFRP1 secreted frizzled-related protein 1
SOX9 SRY (sex determining region Y)-box 9
TFRC transferrin receptor
WT1 Wilms tumor 1
ZMIZ1 zinc finger, MIZ-type containing 1