BRD-A35033682_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A35033682_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AK4 adenylate kinase 4
AMDHD2 amidohydrolase domain containing 2
ANOS1 anosmin 1
BHLHE41 basic helix-loop-helix family, member e41
C1S complement component 1, s subcomponent
CD58 CD58 molecule
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN18 claudin 18
CLU clusterin
DIRAS3 DIRAS family, GTP-binding RAS-like 3
ETV5 ets variant 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FAM129A family with sequence similarity 129, member A
FAM134A family with sequence similarity 134, member A
GSTA4 glutathione S-transferase alpha 4
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IL1R2 interleukin 1 receptor, type II
KAZN kazrin, periplakin interacting protein
KDM5D lysine (K)-specific demethylase 5D
KLK11 kallikrein-related peptidase 11
MAT2A methionine adenosyltransferase II, alpha
MSMO1 methylsterol monooxygenase 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAT plasminogen activator, tissue
PPAP2B phosphatidic acid phosphatase type 2B
PTN pleiotrophin
RNF167 ring finger protein 167
SATB1 SATB homeobox 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
STC1 stanniocalcin 1
SYNM synemin, intermediate filament protein
TNC tenascin C
TNS1 tensin 1
TSPAN8 tetraspanin 8
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOH apolipoprotein H (beta-2-glycoprotein I)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CAST calpastatin
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CRIP1 cysteine-rich protein 1 (intestinal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DERA deoxyribose-phosphate aldolase (putative)
ECH1 enoyl CoA hydratase 1, peroxisomal
ECM1 extracellular matrix protein 1
EIF5B eukaryotic translation initiation factor 5B
FAM69A family with sequence similarity 69, member A
FNTA farnesyltransferase, CAAX box, alpha
FOLR1 folate receptor 1 (adult)
GRB7 growth factor receptor-bound protein 7
HIST1H2BG histone cluster 1, H2bg
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MECOM MDS1 and EVI1 complex locus
MFAP5 microfibrillar associated protein 5
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
ORM1 orosomucoid 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
RAI14 retinoic acid induced 14
RGCC regulator of cell cycle
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
ZNF395 zinc finger protein 395