BRD-A35033682_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-A35033682_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA1 carbonic anhydrase I
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CST1 cystatin SN
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GCLM glutamate-cysteine ligase, modifier subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
KIAA0226L KIAA0226-like
MME membrane metallo-endopeptidase
MMP3 matrix metallopeptidase 3
PCP4 Purkinje cell protein 4
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
TSPYL5 TSPY-like 5
TXNRD1 thioredoxin reductase 1
VCAM1 vascular cell adhesion molecule 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ATF3 activating transcription factor 3
BST2 bone marrow stromal cell antigen 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
FABP4 fatty acid binding protein 4, adipocyte
FAIM Fas apoptotic inhibitory molecule
GPR183 G protein-coupled receptor 183
INPP5F inositol polyphosphate-5-phosphatase F
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2