BRD-A34817987_-666_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A34817987_-666_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
C6ORF62 chromosome 6 open reading frame 62
CAST calpastatin
CAV2 caveolin 2
CCL19 chemokine (C-C motif) ligand 19
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD9 CD9 molecule
CFD complement factor D (adipsin)
CLCA4 chloride channel accessory 4
CLU clusterin
COCH cochlin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DLD dihydrolipoamide dehydrogenase
DUOX2 dual oxidase 2
DUSP5 dual specificity phosphatase 5
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GPNMB glycoprotein (transmembrane) nmb
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
KRT13 keratin 13, type I
KRT15 keratin 15, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
OLFM4 olfactomedin 4
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PSAP prosaposin
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A13 S100 calcium binding protein A13
SERINC5 serine incorporator 5
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYNM synemin, intermediate filament protein
TMSB15A thymosin beta 15a
TRIB3 tribbles pseudokinase 3
TSPAN13 tetraspanin 13
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UPP1 uridine phosphorylase 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XPO7 exportin 7

decreased expression

Symbol Name
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
BEX1 brain expressed, X-linked 1
CLIC4 chloride intracellular channel 4
COL5A2 collagen, type V, alpha 2
CXCL8 chemokine (C-X-C motif) ligand 8
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HAL histidine ammonia-lyase
HOXB2 homeobox B2
MSRB1 methionine sulfoxide reductase B1
NQO1 NAD(P)H dehydrogenase, quinone 1
TFF3 trefoil factor 3 (intestinal)
TSPAN3 tetraspanin 3
ZNF586 zinc finger protein 586