BRD-A34806832_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-A34806832_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANXA3 annexin A3
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
ARHGAP29 Rho GTPase activating protein 29
ATF1 activating transcription factor 1
ATF3 activating transcription factor 3
BEX1 brain expressed, X-linked 1
C1S complement component 1, s subcomponent
CCL20 chemokine (C-C motif) ligand 20
CD99 CD99 molecule
CFI complement factor I
CHIC2 cysteine-rich hydrophobic domain 2
CPM carboxypeptidase M
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CTSB cathepsin B
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOSC4 exosome component 4
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP14 FK506 binding protein 14, 22 kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GPX3 glutathione peroxidase 3
H1F0 H1 histone family, member 0
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JUND jun D proto-oncogene
KLF9 Kruppel-like factor 9
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MSX1 msh homeobox 1
MT1F metallothionein 1F
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHACTR2 phosphatase and actin regulator 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PSPH phosphoserine phosphatase
PTGDS prostaglandin D2 synthase 21kDa (brain)
RCAN1 regulator of calcineurin 1
RGS1 regulator of G-protein signaling 1
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35F2 solute carrier family 35, member F2
SLPI secretory leukocyte peptidase inhibitor
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
C3ORF14 chromosome 3 open reading frame 14
C6ORF62 chromosome 6 open reading frame 62
CCNB1 cyclin B1
CCNF cyclin F
CDC25B cell division cycle 25B
CECR1 cat eye syndrome chromosome region, candidate 1
CHGB chromogranin B
COL3A1 collagen, type III, alpha 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FGL2 fibrinogen-like 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAREM GRB2 associated, regulator of MAPK1
GJA1 gap junction protein, alpha 1, 43kDa
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IGKC immunoglobulin kappa constant
ITGB1BP1 integrin beta 1 binding protein 1
KLHL21 kelch-like family member 21
MMP12 matrix metallopeptidase 12
OXA1L oxidase (cytochrome c) assembly 1-like
PFN2 profilin 2
PIP prolactin-induced protein
PRR7 proline rich 7 (synaptic)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
QPCT glutaminyl-peptide cyclotransferase
SOX4 SRY (sex determining region Y)-box 4
SPON1 spondin 1, extracellular matrix protein
STARD7 StAR-related lipid transfer (START) domain containing 7
TGFA transforming growth factor, alpha
TRIB2 tribbles pseudokinase 2
TUBB2A tubulin, beta 2A class IIa
TXNDC9 thioredoxin domain containing 9
ZIC1 Zic family member 1