BRD-A34205397_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-A34205397_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CFB complement factor B
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FADS1 fatty acid desaturase 1
FGF13 fibroblast growth factor 13
G6PD glucose-6-phosphate dehydrogenase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL17RB interleukin 17 receptor B
INSIG1 insulin induced gene 1
L1CAM L1 cell adhesion molecule
LAMA5 laminin, alpha 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MSMB microseminoprotein, beta-
PDE2A phosphodiesterase 2A, cGMP-stimulated
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SQLE squalene epoxidase
STX1A syntaxin 1A (brain)
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
CCND2 cyclin D2
CD69 CD69 molecule
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KANK1 KN motif and ankyrin repeat domains 1
MMP12 matrix metallopeptidase 12
PDE4B phosphodiesterase 4B, cAMP-specific
POSTN periostin, osteoblast specific factor
PTCH1 patched 1
RCAN1 regulator of calcineurin 1
SPRR3 small proline-rich protein 3