BRD-A33833419_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-A33833419_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
BAG3 BCL2-associated athanogene 3
CLIP3 CAP-GLY domain containing linker protein 3
CTSZ cathepsin Z
CUX1 cut-like homeobox 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5D lysine (K)-specific demethylase 5D
KIF5C kinesin family member 5C
KLF4 Kruppel-like factor 4 (gut)
LOX lysyl oxidase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PFKP phosphofructokinase, platelet
PIR pirin (iron-binding nuclear protein)
PLCB4 phospholipase C, beta 4
PXMP2 peroxisomal membrane protein 2, 22kDa
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TIMP3 TIMP metallopeptidase inhibitor 3
TUSC3 tumor suppressor candidate 3
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCDC86 coiled-coil domain containing 86
CCND2 cyclin D2
CD24 CD24 molecule
CFD complement factor D (adipsin)
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DCT dopachrome tautomerase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPCAM epithelial cell adhesion molecule
FGB fibrinogen beta chain
GPM6B glycoprotein M6B
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT19 keratin 19, type I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
NFIB nuclear factor I/B
NKG7 natural killer cell granule protein 7
PERP PERP, TP53 apoptosis effector
PIP prolactin-induced protein
RND3 Rho family GTPase 3
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SNX10 sorting nexin 10
SOD2 superoxide dismutase 2, mitochondrial
TF transferrin
TGFBR3 transforming growth factor, beta receptor III
XIST X inactive specific transcript (non-protein coding)