BRD-A32595718_CVF-CSC-7 BRD-A32595718_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-A32595718_CVF-CSC-7 BRD-A32595718_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
APOD apolipoprotein D
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BZW2 basic leucine zipper and W2 domains 2
CBS cystathionine-beta-synthase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRDL1 chordin-like 1
CLU clusterin
COLEC12 collectin sub-family member 12
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FAM129A family with sequence similarity 129, member A
FLOT1 flotillin 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA6 GATA binding protein 6
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSN gelsolin
IFITM1 interferon induced transmembrane protein 1
IFRD1 interferon-related developmental regulator 1
IGFBP7 insulin-like growth factor binding protein 7
IGKV4-1 immunoglobulin kappa variable 4-1
IL17RB interleukin 17 receptor B
INSIG1 insulin induced gene 1
KLF9 Kruppel-like factor 9
LAP3 leucine aminopeptidase 3
MGLL monoglyceride lipase
MTSS1 metastasis suppressor 1
NFIL3 nuclear factor, interleukin 3 regulated
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDLIM1 PDZ and LIM domain 1
PLA2G16 phospholipase A2, group XVI
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
STC2 stanniocalcin 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AK1 adenylate kinase 1
BAD BCL2-associated agonist of cell death
CA2 carbonic anhydrase II
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
DLK1 delta-like 1 homolog (Drosophila)
DUSP22 dual specificity phosphatase 22
EMP3 epithelial membrane protein 3
FCGBP Fc fragment of IgG binding protein
FERMT1 fermitin family member 1
GLIPR1 GLI pathogenesis-related 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KRT7 keratin 7, type II
LTBP3 latent transforming growth factor beta binding protein 3
LZTFL1 leucine zipper transcription factor-like 1
MTDH metadherin
PDGFA platelet-derived growth factor alpha polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PSD3 pleckstrin and Sec7 domain containing 3
RNASET2 ribonuclease T2
SEPW1 selenoprotein W, 1
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SLPI secretory leukocyte peptidase inhibitor
TCTN1 tectonic family member 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta