BRD-A31575449_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

21 genes differentially expressed following the BRD-A31575449_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CPB1 carboxypeptidase B1 (tissue)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
NCALD neurocalcin delta
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

decreased expression

Symbol Name
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LAMP5 lysosomal-associated membrane protein family, member 5
LPL lipoprotein lipase
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TIMP3 TIMP metallopeptidase inhibitor 3
XIST X inactive specific transcript (non-protein coding)