BRD-A28746609_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

187 genes differentially expressed following the BRD-A28746609_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
BEX1 brain expressed, X-linked 1
CA2 carbonic anhydrase II
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CLC Charcot-Leyden crystal galectin
COCH cochlin
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTGF connective tissue growth factor
CUX2 cut-like homeobox 2
DEFA4 defensin, alpha 4, corticostatin
DENND5A DENN/MADD domain containing 5A
EPAS1 endothelial PAS domain protein 1
EREG epiregulin
FNBP1 formin binding protein 1
FSTL1 follistatin-like 1
FTH1 ferritin, heavy polypeptide 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GJA1 gap junction protein, alpha 1, 43kDa
GSN gelsolin
HIST1H2BC histone cluster 1, H2bc
HIST1H2BG histone cluster 1, H2bg
HOMER3 homer scaffolding protein 3
IGFBP7 insulin-like growth factor binding protein 7
INHBB inhibin, beta B
IQCE IQ motif containing E
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
JMJD6 jumonji domain containing 6
KIAA0226L KIAA0226-like
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MT1E metallothionein 1E
NCF1C neutrophil cytosolic factor 1C pseudogene
NPTX2 neuronal pentraxin II
NRIP3 nuclear receptor interacting protein 3
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF1 PHD finger protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN2 reticulon 2
S100A12 S100 calcium binding protein A12
SDC3 syndecan 3
SEC62 SEC62 homolog (S. cerevisiae)
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SNX10 sorting nexin 10
SPARCL1 SPARC-like 1 (hevin)
TCF3 transcription factor 3
TCL1A T-cell leukemia/lymphoma 1A
TNNT1 troponin T type 1 (skeletal, slow)
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TUBA4A tubulin, alpha 4a
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZIC1 Zic family member 1
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALG8 ALG8, alpha-1,3-glucosyltransferase
ANXA9 annexin A9
ARF1 ADP-ribosylation factor 1
ASCL1 achaete-scute family bHLH transcription factor 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BACE2 beta-site APP-cleaving enzyme 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C2CD5 C2 calcium-dependent domain containing 5
C8ORF4 chromosome 8 open reading frame 4
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CFB complement factor B
COPS7A COP9 signalosome subunit 7A
CPNE3 copine III
CYB5A cytochrome b5 type A (microsomal)
DCTN5 dynactin 5 (p25)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EAPP E2F-associated phosphoprotein
EED embryonic ectoderm development
EMG1 EMG1 N1-specific pseudouridine methyltransferase
FAR2 fatty acyl CoA reductase 2
FEN1 flap structure-specific endonuclease 1
FGG fibrinogen gamma chain
FOXJ3 forkhead box J3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA3 GATA binding protein 3
GNPDA1 glucosamine-6-phosphate deaminase 1
H2AFX H2A histone family, member X
HADH hydroxyacyl-CoA dehydrogenase
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
KDM5D lysine (K)-specific demethylase 5D
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT7 keratin 7, type II
LARP4B La ribonucleoprotein domain family, member 4B
M6PR mannose-6-phosphate receptor (cation dependent)
MAGED1 melanoma antigen family D1
MAP7 microtubule-associated protein 7
MBP myelin basic protein
MCM6 minichromosome maintenance complex component 6
MELK maternal embryonic leucine zipper kinase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MUC1 mucin 1, cell surface associated
NET1 neuroepithelial cell transforming 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH2 notch 2
NQO1 NAD(P)H dehydrogenase, quinone 1
PCNA proliferating cell nuclear antigen
PEG10 paternally expressed 10
PEX11B peroxisomal biogenesis factor 11 beta
PGD phosphogluconate dehydrogenase
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTBP3 polypyrimidine tract binding protein 3
RCAN1 regulator of calcineurin 1
RNASE4 ribonuclease, RNase A family, 4
RNMT RNA (guanine-7-) methyltransferase
RRM2 ribonucleotide reductase M2
S100A14 S100 calcium binding protein A14
SEPT2 septin 2
SGCE sarcoglycan, epsilon
SIAH2 siah E3 ubiquitin protein ligase 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMAD1 SMAD family member 1
SORBS2 sorbin and SH3 domain containing 2
SOX4 SRY (sex determining region Y)-box 4
SPEN spen family transcriptional repressor
SRP54 signal recognition particle 54kDa
SRSF1 serine/arginine-rich splicing factor 1
STAG2 stromal antigen 2
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TM4SF1 transmembrane 4 L six family member 1
TM9SF2 transmembrane 9 superfamily member 2
TM9SF4 transmembrane 9 superfamily protein member 4
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM97 transmembrane protein 97
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TPI1 triosephosphate isomerase 1
TUBB tubulin, beta class I
TUG1 taurine up-regulated 1 (non-protein coding)
TXNDC9 thioredoxin domain containing 9
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGCG UDP-glucose ceramide glucosyltransferase
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
XBP1 X-box binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon