BRD-A27554692_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-A27554692_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CST6 cystatin E/M
CSTA cystatin A (stefin A)
CYB5A cytochrome b5 type A (microsomal)
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFI27 interferon, alpha-inducible protein 27
KRT14 keratin 14, type I
KRT15 keratin 15, type I
LIMCH1 LIM and calponin homology domains 1
LY6D lymphocyte antigen 6 complex, locus D
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SCGB2A2 secretoglobin, family 2A, member 2
STC2 stanniocalcin 2
TMEM45A transmembrane protein 45A
TSKU tsukushi, small leucine rich proteoglycan
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
C1ORF54 chromosome 1 open reading frame 54
CPE carboxypeptidase E
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
MSMB microseminoprotein, beta-
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RGS5 regulator of G-protein signaling 5
SCD stearoyl-CoA desaturase (delta-9-desaturase)