BRD-A26095496_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A26095496_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BSG basigin (Ok blood group)
C10ORF10 chromosome 10 open reading frame 10
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DDIT4 DNA-damage-inducible transcript 4
DPP4 dipeptidyl-peptidase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EPAS1 endothelial PAS domain protein 1
FAM69A family with sequence similarity 69, member A
FOLR1 folate receptor 1 (adult)
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HOPX HOP homeobox
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
JADE2 jade family PHD finger 2
LPL lipoprotein lipase
MAOA monoamine oxidase A
MZB1 marginal zone B and B1 cell-specific protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PBX3 pre-B-cell leukemia homeobox 3
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SDC4 syndecan 4
SFTPB surfactant protein B
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SSBP2 single-stranded DNA binding protein 2
TIMP3 TIMP metallopeptidase inhibitor 3
XIST X inactive specific transcript (non-protein coding)
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AXL AXL receptor tyrosine kinase
BASP1 brain abundant, membrane attached signal protein 1
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CPVL carboxypeptidase, vitellogenic-like
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DEFB1 defensin, beta 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
G0S2 G0/G1 switch 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GREB1 growth regulation by estrogen in breast cancer 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KRT13 keratin 13, type I
L1CAM L1 cell adhesion molecule
MARCKS myristoylated alanine-rich protein kinase C substrate
NCALD neurocalcin delta
NET1 neuroepithelial cell transforming 1
NRIP1 nuclear receptor interacting protein 1
OLFM1 olfactomedin 1
OLFM4 olfactomedin 4
PI3 peptidase inhibitor 3, skin-derived
PLAT plasminogen activator, tissue
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNMAL1 paraneoplastic Ma antigen family-like 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A7 S100 calcium binding protein A7
SLC25A46 solute carrier family 25, member 46
SORD sorbitol dehydrogenase
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TMEM47 transmembrane protein 47
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN7 tetraspanin 7